He performed postdoctoral research on the use of adenovirus and retrovirus vectors for treatment of liver disorders. Hoeben graduated in Biology from Utrecht University (1986) and obtained his PhD at Leiden University in 1991. “How not to be seen: immune-evasion strategies in gene therapy” Professor and Head of the Virus and Stem Cell Biology lab, Molecular Cell Biology Department, Leiden University Medical Center, Leiden, The Netherlands In this talk, I will review different mathematical and computational approaches that have contributed to our understanding of the immune system. Multidisciplinary projects combining experimental and mathematical approaches have enhanced general immunological knowledge and are clearly needed to analyze accurately the increase amount of data generated by experimental laboratories. Some of her most recent projects involve modeling cell homeostasis in human, defining the optimal time of maternal vaccination for RSV infection and determining endotypes of atopic dermatitis patients based on serum biomarkers measured by Luminex.Ībstract: Since the 90’s, mathematics has helped to understand immunological and infectious mechanisms, and fields of research such as computational biology, bioinformatics, biostatistics and quantitative immunology have attracted more attention in the experimental research field. She collaborates with many groups on multidisciplinary projects that aim to close the gap between experimental and theoretical work by using biostatistics, bioinformatics and computational approaches. Since 2014, she is a full-time researcher within the Bioinformatics Core Facility in the Laboratory of Translational Immunology of the UMC Utrecht. Her research focused on quantifying cell dynamics in health and disease using mathematical modeling to analyse stable-isotope labeling experiments. Rob de Boer in the Utrecht Center for Quantitative Immunology at Utrecht University. From 2010 to 2014, she performed postdoctoral research in computational and quantitative immunology under the supervision of José Borghans in the Department of Immunology at the UMC Utrecht and collaborated with Prof. She obtained her PhD in biostatistics at Bordeaux University (France) in 2009. Julia Drylewicz was trained in Biostatistics and Epidemiology at Bordeaux School of Public Health and graduated in Biomathematics from Paris V University (France) in 2006. Laboratory of Translational Immunology, University Medical Center, Utrecht, The Netherlandsĭr. Cliona O’Farrellyīelow you can find the speakers who were invited for this Symposium. The programme of the symposium is shown below. The symposium took place on the 17 th and 18 th of November 2016. The topics covered were chosen to keep track of the variety and the latest advancements in these fields in order to stimulate creativity of the audience as they will become the leading front of future research. Round 6 of the RGF will open for applications in the summer.This symposium aimed to broaden knowledge in fields related to infection and immunity and techniques that are less commonly known. Total RGF support in the North West from Round 1 to 5 has totalled £420m across 79 projects and programmes. Unilever will use the funding to grow its product design capabilities in Port Sunlight, working closely with the University of Liverpool, University of Manchester and Sci-Tech Daresbury.ĭeputy Prime Minister Nick Clegg will today be visiting two of the companies supported by the RGF, Glen Dimplex and Round 4 beneficiary Tratos. Glen Dimplex is planning to increase its manufacturing commitment in Merseyside for brands such as Stoves, Belling and New World, and develop medical refrigeration appliances.Ībsynth Biologics will use the funding for the next phases of its research and development activity in developing vaccines to treat bacterial infections. GT Energy will use the funds to progress its geothermal scheme at Devonshire Street in Manchester. North West Logistics, which provides storage and transport services to a range of blue-chip companies across Europe, will build a new facility to expand its specialist hazardous product division. Redx Pharma will create a new pharmaceutical research and development centre for metabolic disease alongside its existing facilities for cancer and infection. Unilever UK Central Resources in Port Sunlight.Absynth Biologics at Alderley Park, Cheshire.The successful bidders in the North West are: The Government believes that its initial investment will lead to a further £140m of private sector investment within the next decade.Ī total of £300m was available for companies across the UK. Seven North West companies have won a share of a £23m pot in the fifth round of the Regional Growth Fund.
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